Rare Disease Database (RDD)

The Rare Disease Database (RDD) is a nationwide, expert-reviewed registry comprising over 18,000 confirmed rare disease cases reported in Taiwan between 2012 and 2022. This database captures clinically validated diagnoses through the Health Promotion Administration. It features standardized variables including diagnostic dates, codes, demographic information, and death status. RDD is structured for direct linkage with Taiwan’s NHIRD, enabling robust longitudinal and real-world analyses. This database serves as a critical foundation for epidemiological studies, rare disease policy evaluation, and orphan drug research.